王征实验室在《Cell Reports》发表题为“Noncoding transcripts are linked to brain resting-state activity in non-human primates”的研究论文,报道了利用实验室前期收集的猕猴全脑分区、单细胞转录组图谱和静息态脑影像数据,整合分析发现150个非编码基因与蛋白编码基因一起共同调控大脑网络在静息状态下的同步自发振...
纳家勇治课题组在《PLOS Biology》期刊上发表题为“Sequential involvements of the perirhinal cortex and hippocampus in the recall of item-location associative memory in macaques”的研究论文,通过猕猴电生理研究揭示了语义记忆提取的两段式机制。方位记忆信息先由鼻周皮质...
岳伟华课题组在《Military Medical Research》在线发表了题为“Prediction of treatment response to antipsychotic drugs for precision medicine approach to schizophrenia: randomized trials and multiomics analysis”的研究,发现并验证了...
岳伟华课题组在《Psychiatry and Clinical Neurosciences 》发表题为“Therapeutic Outcomes Wide Association Scan of different antipsychotics in patients with schizophrenia: randomized clinical trials and multi-ancestry...
邹鹏课题组在《Nature Communications》发表题为“Genetically encoded photocatalytic protein labeling enables spatially-resolved profiling of intracellular proteome”的研究论文,报道了一种基因编码的可见光催化时空分辨蛋白质组邻近标记新技术。
黄卓课题组在《eLife》期刊在线发表了题为“Coupling of Slack and Nav1.6 sensitizes Slack to quinidine blockade and guides anti-seizure strategy development”的研究成果,发现电压门控钠离子通道Nav1.6和钠离子激活的钾离子通道Slack之间的功能和物理耦连,两通道耦连显著增强了Sla...
陈良怡课题组在《Nature Communications》发表了题为“Quantitative structured illumination microscopy via a physical model-based background filtering algorithm reveals actin dynamics”的研究论文。通过仔细研究结构光显微镜的成像过程,提出基于物理成像模型的...
吴思实验室在《eLife》发表题为“Firing rate adaptation affords place cell theta sweeps, phase precession and procession”的研究成果,利用连续吸引子神经网络(CANN)加上神经元的适应性反应(adaptation)对海马区位置细胞进行建模,阐明了神经生物学实验所发现的海马位置细胞形成theta sweeps和...
饶毅实验室在《eLife》发表题为“Importance of glutamine in synaptic vesicles revealed by functional studies of SLC6A17 and its mutations pathogenic for intellectual disability”的研究论文,报道了功能研究SLC6A17转运蛋白及其导致智力障碍突变揭示突触...
陆林课题组在Science Bulletin合作发表题为“China Brain Project: from bench to bedside”的专家评介文章,从脑图谱、类脑计算与脑机智能、脑疾病防治等角度介绍了各国脑计划,特别是中国脑计划的特色,其中重点介绍了中国脑计划在脑疾病临床研究大数据与样本库平台的建设情况,并指出了整体推进过程中面临的挑战。